Pharmacokinetics and Bioequivalence Comparison of 600 mg Single-Dose Linezolid Oral Suspension and Tablet Formulation in Healthy Chinese Subjects
نویسندگان
چکیده
Abbreviations: AE: Adverse Event; AUC: Area under Plasma Concentration–time Curve; AUCinf: Area under Plasma Concentration-time Curve from Time Zero Extrapolated to Infinite Time; AUClast: Area under Plasma Concentration–time Curve from Time Zero to the Time of the Last Quantifiable Concentration; BMI: Body Mass Index; CI: Confidence Interval; Cmax: Maximum Plasma Concentration; CRU: Clinical Research Unit; CYP: Cytochrome P450; ECG: Electrocardiogram; HPLC-MS/MS: High-performance Liquid Chromatography Tandem Mass Spectrometry; LLOQ: Lower Limit of Quantification; PD: Pharmacodynamics; PK: Pharmacokinetic; SD: Standard Deviation; t1/2: Elimination Half-life; Tmax: Time for Maximum Plasma Concentration
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